Patophysiology of articular cartilage in elderly
نویسندگان
چکیده
Background Osteoarthritis is a degenerative disease involving diarthrosis articulations. The evolution of the disease is very slow; the first changes regard the cellmatrix morpho-functional unit of articular cartilage called chondron by Benninghoff. The articular cartilage modifications are progressive from the superficial layer through the intermedial and the deep layer. Authors analyzed the ultrastructural changes of articular cartilage in the elderly, step by step from chondron modifications to macroscopic degenerative changes of the arthrosis.
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